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Ongoing partial clinical trials
| Drug | Indication | Popular topics in drug trials |
JRF101 | NSCLC （non small cell lung cancer） | Phase I clinical trial of clinical safety, tolerability and pharmacokinetics for injection and honokiol liposome (HK) in patients with advanced malignant solid tumors. |
JRF102 (XH-6003 Injection, NKCC Inhibitor) | For the treatment of cerebral edema of various etiologies, to reduce intracranial pressure and prevent cerebral herniation. | A Randomized, Double-blind, Single-center, Placebo-controlled, Dose-escalating Phase I Clinical Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single Doses of XH-6003 Injection in Healthy Adult Chinese Subjects. |
JRF103 （An irreversible pan-her tyrosine kinase inhibitor） | Advanced solid tumor | An open, multicenter, phase I/II clinical study to evaluate the safety, tolerability, pharmacokinetic characteristics, and initial efficacy of JRF103 tablets in patients with advanced solid tumors. |
JRF104 (XH-30002 Capsule, CDK4 Inhibitor) | Advanced Solid Tumors | A Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetic Profiles and Preliminary Efficacy of Orally Administered XH-30002 Capsules in Patients with Advanced Solid Tumors. |
JRF105 (XH-5102 Tablets, JAK2 Inhibitor) | Myeloproliferative Neoplasms | A Phase I/II Study to Evaluate the Safety, Tolerability, Pharmacokinetic Profiles and Preliminary Efficacy of Orally Administered XH-5102 Tablets in Patients with Myeloproliferative Neoplasms. |